2/20/2012 - 9th Annual Postdoctoral Research Day

9th Annual Postdoctoral Research Day 2012 

Monday, February 20, 2012

9:00 am – 5:00 pm

West Pavilion Conference Rooms

Located on the second floor of UAB Hospital in the Spain Wallace Building 

Abstract Deadline:  January 20 

Submit your 300 word abstract with your name, mentor, title of your abstract, authors/contributors, and your department to

*You must carbon copy (cc) your mentor for submission to be valid.

Rules for entry @ under News & Events

Light breakfast & Lunch will be served


Session 1:  Sponsored by Comprehensive Diabetes Center



Maria Hopkins, Department of Psychology

Mathieu Lesort, Department of Psychiatry

Inga Kadish, Department of Cell Biology


9:30 – 9:35         Welcome by Teruko Bredemann, Executive Board Member, UAB Postdoctoral Association


9:35 – 9:50         Maria D. Rubio

Abnormalities of the Duo/Rac-1/PAK1Pathway drive myosin light chain phosphorylation in frontal cortex in schizophrenia


9:50 – 10:05       Qin Li

Understanding the activity-dependent regulation of NPY interneurons that leads to neuropeptide Y release in the hippocampal CA1 circuit


10:05 – 10:20     Anthony J. Filiano

Progranulin deficiency in neurons causes frontotemporal dementia-related dysfunction independent of neuroinflammation


10:20 – 10:45     Keri A. Barksdale

An examination of vesicular glutamate transporter (vGLUT) terminals in the postmortem human striatum: a light and electron microscopic study


10:45 – 10:55     Coffee Break


10:55 – 11:10     Amy J. Knight

                           Functional connectivity and financial capacity in Alzheimer’s disease


11:10 – 11:25     Aundrea F. Bartley

Alterations in the E to I balance in PGC-1α deficient mice are caused by dysfunction of inhibition from perisomatic targeting interneurons


11:25 – 11:40     Rodolphe Nenert

Modulations of ongoing alpha oscillations predict successful short-term visual memory encoding


11:40 – 11:55     Keun W. Park

Protective role of STAT3 in NMDA-induced neuronal death: Negative regulatory effect of SOCS3

Session 2:  Sponsored by Nutrition & Obesity Research Center (NORC)



Michael Brooks, Department of Education

Heidi Erlandsen, Department of Periodontology

Gwendalyn King, Department of Neurobiology


9:30 – 9:35         Welcome by Jessica Perez, Executive Board Member, UAB Postdoctoral



9:35 – 9:50         Anandi Sawant

Myeloid-derived suppressor cells function as osteoclast progenitors enhancing bone destruction in breast cancer


9:50 – 10:05       Angel A. Alvarez

                           The role of NF-κB in glioblastoma and cancer stem cells


10:05 – 10:20     Jessica M. Grunda

Development and characterization of novel murine models of

medulloblastoma bone metastasis


10:20 – 10:45     Maria Azrad

Flaxseed-derived omega-3 fatty acids and lignan reduce cell growth, inflammation and angiogenesis in men with prostate cancer


10:45 – 10:55     Coffee Break


10:55 – 11:10     Tabitha M. Hardy

ER-α reactivation occurs later in African American breast cancer cell lines treated with chemopreventive dietary phytochemicals EGCG and sulforaphane


11:10 – 11:25     Larissa Sweeny

Inhibition of cervical lymph node metastasis by CD147 in an orthotopic base of tongue squamous cell carcinoma implantation model


11:25 – 11:40     James J. Cody

Development of novel models of breast cancer brain metastasis for the evaluation of oncolytic herpes simplex viral therapy


11:40 – 11:55     Vladimir Ternovoy

Inhibition of tumor cell proliferation/viability by apolipoprotein mimetic peptides





Session 3:  Sponsored by the Comprehensive Arthritis, Musculoskeletal,

and Autoimmunity Center



Shahid Mukhtar, Department of Biology

Mohammad Hassan, Department of Oral & Maxillofacial Surgery

Sasanka Ramanadham, Department of Physiology & Biophysics


9:30 – 9:35         Welcome by LaToya Paul, Executive Board Member, UAB Postdoctoral Association


9:35 – 9:50         Jiri Vlach

Structural determinants of HIV-1 Gag interaction with the host plasma membrane


9:50 – 10:05       Benjamin S. Christmann

Recognition of gut microbiota antigens in the development of autoimmune diabetes in NOD mice


10:05 – 10:20     Preston E. Bratcher

                           Effects of MMP-9-mediated cleavage of SP-D in vitro


10:20 – 10:45     Tracy Hwangpo

Phenotypic analysis of various B cell populations in common variable immunodeficiency, recurrent sino-pulmonary infection, and immunoglobulin deficient patients


10:45 – 10:55     Coffee Break


10:55 – 11:10     Srilalitha Kuruganti

                           Quantitative detection of Interferon-α subtypes in lupus patients


11:10 – 11:25     Rakesh K. Bakshi

IL-2 production by anti-viral CD8 T cells predicts the formation of immunological memory


11:25 – 11:40     Subhashini Bolisetty

Regulation of macrophage polarization by Heme oxygenase-1 in obstructive nephropathy


11:40 – 11:55     Taegyu Choi

                           Effect of doxorubicin on mitophagy in THP-1 monocytes



Session 4:  Sponsored by the Biomatrix Engineering and Regenerative Medicine Center (BERM) and the Gregory Fleming James Cystic Fibrosis Research Center


Ilan Kerman, Department of Psychiatry

Gregory A. Clines, Department of Medicine

Thomas Van Groen, Department of Cell Biology


1:00 – 1:05         Welcome by Hope Amm, Executive Board Member, UAB Postdoctoral Association


1:05 – 1:20         Emily J. Dhurandhar

                           Clinical utility of whole genome prediction for personalized medicine


1:20 – 1:35         Tonya Breaux-Shropshire

                           Relationship of self-blood pressure monitoring, medication adherence, self-efficacy, stage of change and blood pressure control among municipal workers with hypertension


1:35 – 1:50         Brooks C. Wingo

                           Behavior change as a mediator between change in self-efficacy and weight loss in a behavioral intervention 


1:50 – 2:05         Rohit Pradhan

                           The impact of competition on nursing home staff turnover


2:05 – 2:20         Henry T. Robertson

                           Turning the analysis of obesity-mortality associations upside down: Modeling years of life lost through conditional distributions 


2:20 – 2:30         Coffee Break

2:30 – 2:45         Gordon Fisher

Aerobic exercise training conserves insulin sensitivity for one year following weight loss in overweight women

2:45 – 3:00         Alexis C. Frazier-Wood

Epidemiological evidence that self-reported heavy daily physical activity improves lipoprotein subclass profile

3:00 – 3:15         Megan E. Ruiter

                           Short sleep predicts stroke symptoms in persons of normal weight


3:15 – 3:30         David Buys

Neighborhood disadvantage increases odds of nursing home admission for older adults with physical impairment


3:30 – 3:45         William B. Hillegass

Cost-effectiveness of new oral antiplatelet agents and testing strategies during early invasive management of acute coronary syndrome patients



Session 5:  Sponsored by the Center for Free Radical Biology



Candace Floyd, Department of Physical Medicine & Rehabilitation

Cathy Fuller, Department of Physiology & Biophysics

Michelle Olsen, Department of Physiology & Biophysics


1:00 – 1:05         Welcome by Jessica Grunda, Executive Board Member, UAB Postdoctoral Association


1:05 – 1:20         Sammeta V. Raju

Cigarette smoke induces systemic defects in cystic fibrosis transmembrane conductance (CFTR) regulator ion transport


1:20 – 1:35         Ashley Filiano

Chronic alcohol consumption disrupts the circadian clock in the liver but not in the suprachiasmatic nucleus


1:35 – 1:50         Stella Aslibekyan

                           APOA1, CETP, and CILP2 variants modify the lipid response to fenofibrate:         Genetics of lipid lowering and diet network


1:50 – 2:05         Guanlan Xu

Verapamil inhibits proapoptotic thioredoxin-interacting protein and prevents beta cell loss in diabetes


2:05 – 2:20         Tanecia Mitchell

Thiol oxidation regulates cellular bioenergetics and mitochondrial dynamics in Type I diabetic pancreatic β-cells


2:20 – 2:30         Coffee Break


2:30 – 2:45         Ceren Yarar

Effects of contractile activity on skeletal muscle glucose uptake signaling in spinal cord-injured vs. able-bodied individuals


2:45 – 3:00         Edward K. Merritt

                           Gene expression of skeletal muscle mass regulators after severe burn injury


3:00 – 3:15         Jisun Lee

                           α-synuclein sensitizes cellular toxicity to mitochondrial toxins


3:15 – 3:30         Michelle M. Bohan Brown

                           Rapid development of hepatic ER stress in critical illness diabetes


3:30 – 3:45         Tomader Ali

Detrimental effects of saturated free fatty acids on pancreatic beta cells: A molecular and imaging analysis


Session 6:  Sponsored by the Center for Aging



David Chaplin, Department of Microbiology

Carmel McNicholas-Bevensee, Department of Physiology & Biophysics

Tara Desilva, Department of Physical Medicine & Rehabilitation


1:00 – 1:05         Welcome by Aundrea Bartley, Executive Board Member, UAB Postdoctoral Association


1:05 – 1:20         Jason Huff

                           Copper homeostasis as a drug target for tuberculosis chemotherapy


1:20 – 1:35         Olga Danilchanka

Identification and role of porins for growth and drug resistance of Mycobacterium tuberculosis


1:35 – 1:50         Baldeep Khare

Group B Streptococcus Sortase C1: structural studies of the “lid” and substrate binding 


1:50 – 2:05         James Daubenspeck

                           Association of polysaccharides with biofilms of Mycoplasma pneumoniae


2:05 – 2:20         Ying Wang

PDGF mediates TGFβ-induced migration during development of the spinous process


2:20 – 2:30         Coffee Break


2:30 – 2:45         Jessica Perez

Effect of transforming growth factor-β (TGF-β) on Sox9 function and chondrocyte phenotype


2:45 – 3:00         Wan-Yu Lin

                           Haplotype-based methods for detecting low-frequency causal variants under GWAS genotyping platforms


3:00 – 3:15         Samad Jahandideh

Comprehensive comparative analysis and identification of RNA-binding protein domains: multi-class classification and feature selection


3:15 – 3:30         Abraham Freiji

                           Global asymptotic stability in a model of biological networks                     


3:30 – 3:45         Open

Examples of Abstracts below:

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